Brief Introduction about NMR

It is known that nuclei with non-zero spin give two energy states when they are situated in strong magnetic field. The electromagnetic wave that corresponds to the difference of the energy states is resonated and absorbed by the nuclei. This is called NMR (Nuclear Magnetic Resonance). MRI (Magnetic Resonance Imaging) uses this principle for the diagnosis of diseases. The frequency of the electromagnetic wave depends on the type of nuclei, the strength of the magnetic field, as well as the electrons distributed around. By analyzing the NMR data, it is possible to predict the distribution of the surrounding electrons and chemical bonds. This enables to determine the molecular structure.

NMR spectrometer is one of the widely used devices for studying organic compounds and biomacromolecules. By contrast with X-ray crystallography, NMR can analyze mobile structures and intermolecular interactions in nearly physiological condition, i.e. in solution state, an environment similar to that in the living cell. For these advantages, NMR is realized as a powerful tool as X-ray crystallography to study protein structures in the post-genome era.


High-field, High-sensitive NMR Spectrometer in the RIKEN NMR Facility


Center NMR Complex

Bruker 800MHz

& cryoprobehead

West NMR Complex